DEPARTMENT OF BIOCHEMISTRY

COIMBATOREMEDICAL COLLEGE,COIMBATORE

History of the department

v  The Biochemistry Department has started functioning separately from Physiology in the college premises since 1967.

v  Biochemistry Laboratory is functioning since 1964 initially in the college premises, later started functioning in  the hospital.

v  We provide emergency services in addition to the regular diagnostic services round the clock

Milestones of the department

 A . Hospital laboratory

     Hospital Biochemistry Laboratory  is functioning since 1964.

     Initially, the hospital lab was equipped with Photoelectric Colorimeter and Centrifuges only .

     Later on during 1996 Semi auto analysers and Flame photometers, automated pipettes,Spectrophotometer were purchased.

     Since 2000, The Fully Automated analyser, Electrolyte analysers [ion selective electrodes] were used for diagnostic works

     Then Thyroid hormones analysis was started using Elisa Reader from 2004.

     Arterial blood gas analysis was done using Blood Gas analyser since 2005.

     The utilization of ISE 4000 Bicarbonate analyser & EM 360 Biochemical analyser commenced from 2009.

     The Reverse osmosis plant was installed in our diagnostic laboratory in 2010.

        We have effective means of Biomedical waste management     

        functioning in our laboratory since 2011

LIST OF SOPHISTICATED INSTRUMENTS FOR BIOCHEMICAL ANALYSIS:

     FULLY AUTOMATED ANALYSER

     SEMI AUTOMATED ANALYSERS

     ELECTROLYTE ANALYSER

     ELISA.READER & WASHER

      ELECTROPHORETIC APPARATUS

     CHROMATOGRAPHY CHAMBER

     HOT AIR OVENS

     WATER.DISTILLATION APPARATUS

     CENTRIFUGES

     FLAME PHOTOMETERS

     BICARBONATE ANALYSER.

     BLOOD GAS ANALYSER

 BIOCHEMICAL  INVESTIGATIONS PERFORMED IN OUR LABORATORY:

   1. Blood glucose

2.     Blood Urea

3.     Serum Creatinine

4.     Serum Total Protein

5.     Serum Albumin : Globulin

6.     Serum Cholesterol

7.     Serum Bilirubin - Total,  Direct

8.     S.G.O.T. (AST)

9.     S.G.P.T. (ALT)

10.Serum Alkaline Phosphatase

11.Serum Acid Phosphatase

12.Serum Calcium

13.Serum Phosphorus

14.Serum Electrolytes(Na+, K+, Cl-, HCO3-, Li)

15.Fluid Analysis (Protein, Sugar, Chloride)

16.Urine - Sodium

17.Glucose Tolerance Test.

18.Clearance Tests -  Urea Clearance, Creatinine Clearance.

19.Cerebro Spinal Fluid Analysis - Sugar,Chloride, Protein..

20.Serum Total CPK, CPK- MB

21..Serum LDH.

22.Serum Triglycerides.

23.Serum Amylase.

24.Serum HDL Cholesterol, VLDL, LDL Cholesterol.

25.Serum Protein Electrophoresis.

26.Screening for Metabolic Disorder - Urine Analysis

27.Analysis of Calculi.

28.Paper Chromatography  - Single &Double Dimension.

29.Thyroid Profile - T3, T4, TSH

30.Blood Gas Analysis- pH,  pO2, pCo2 , Base excess

COIMBATORE MEDICAL COLLEGE HOSPITAL

AUTOMATED ANALYSERS

                                                                BIOCHEMISTRY LABORATORY

      BIOCHEMISTRY DEPARTMENT STATISTICS (INVESTIGATIONS)

 
















   
 B- Academic activities in the college:

FACULTIES ACCORDING TO MCI NORMS:

PROFESSOR                                  : ONE
ASSOCIATE PROFESSOR              : ONE
ASSISTANT PROFESSORS            : TWO
TUTORS                                          : THREE

We have Lecture hall accommodating 200 students, Equipped with LCD Projector and audio visual aids.

Our Practical Laboratory which accommodates 90 Students, has Central gas connection since 2010 and granite top were laid for the practical Work Tables in the student and Research Lab during 2011.

a)M.B.B.S course:                             Student seatallotment-150

Thestudents intake has been increased to 150 from the year 2004.

The theory and practical hours allotted per year is 240 hours which includes theory lectures, discussions, seminars etc.

AUDIOVISUAL AIDS
  The Department is now equipped withthe following instruments, to aid in Teaching and Analytical work like

L C D

Computers

Lap Top

Slide Projector and

Over Head Projector

ACADEMIC ACTIVITIES

Facilitation of acquiring   knowledge in the following Areas-

• Cell organisation, transport, signals
•  Nutrition, minerals, vitamins
• Molecular biology, genetic mutations ,recombinant DNA , gene  therapy etc
• Enzymes, role in metabolism.
• Proteins of transport & defence, disorders
• Metabolism of carbohydrates, lipids, proteins & disorders
• Organ function tests of liver, kidney, thyroid, pancreas, adrenal gland.
• Hormonal actions and mechanisms
• Analysis of biochemical parameters in diagnosis of diseases

 TEACHING METHODS   INCLUDE   ( 240hours)

  LECTURES

 DISCUSSIONS

  DEMONSTRATIONS

  SEMINARS 

  INTEGRATEDTEACHING-HORIZONTAL& VERTICAL

      EVALUATION OF THESTUDENTS  IS DONE BY

   INTERNAL ASSESSMENT TESTS

  PRACTICAL TESTS

  VIVA VOCE

  ASSIGNMENTS

CME Programme conducted by our Department- 0n 26.3.2011

TOPIC : An update on Renal Function tests and  interpretations

 We Conducted BioQuiz for theFirst M.B.B.S Students and Prizes for the Winners and Certificates for theParticipants were distributed.

2.D.PHARMACY  COURSE:           200 hours     Student seat allotment- 60

     This course was started from the year 1991 .

     Theory lectures and practical  training are given to the students in theallotted 200 hours for Biochemistry.

    TEACHING   by LECTURES  & PRACTICAL CLASSES on the following aspects.

 Basics of  chemistry, metabolisms ofCarbohydrates,Lipids,Proteins,In born Errors,  Enzymolgy, Nutrition, Diagnostic Instruments,Function Tests, clinical Correlations.

 Practical procedures ofanalysis of solutions, urine, blood parameters Reagent preparations, Demonstrationof Instrument functioning etc.
  Evaluation   of students is done by periodical theory and practical tests and           

  University examination   -Theory  &   Practical   at the end of the Year.

 3. D.M.L.T  COURSE :    200 HOURS  PER YEAR- Student seat allotment-100

In the year 2004 the C.M.L.T course was started. 

D.M.L.T course was started from the year 2005.

About 100 students are trained in laboratory technology every year.

Theory lectures and practical training are given to the students in the allotted hours for Biochemistry and paraclinical training in the diagnostic works at the hospital

 Basics of chemistry,metabolisms of Carbohydrates, Lipids, Proteins, In born Errors, Enzymolgy,Nutrition, Diagnostic Instruments, Function Tests., clinical  Correlations. Practical proceduresof analysis of solutions,urine,blood parameters, Reagent preparations,Standardisation of Reagents, preservation of samples

  Diagnostic procedures inthe hospital Laboratory are included in the syllabus.

            Evaluation   of students is done by     periodicaltheory and practical tests                          

            Universityexamination   -Theory   &  Practical   at the end of the 2 ndYear.

1.    PARAMEDICAL COURSE -10 HRS    

 Basics of    chemistry,metabolisms of Carbohydrates, Lipids, Proteins

 In born Errors ,  Enzymolgy,  Nutrition, Diagnostic Instruments, Function Tests., clinical Correletions are enlightened.

RESEARCH  WORK - (on going projects)

1. Arterial Blood Gas Analysis in Renal Diseases  - study in population  treated in  C.M.C.H.
2. Acid Phosphatase in Prostatic Enlargement - study in population  treated in  C.M.C.H.

      3.   Thyroid, lipid profiles and infertile-study in population treated in C.M.C.H.