::Departments : Pre - Clinical : Biochemistry

DEPARTMENT OF BIOCHEMISTRY

COIMBATORE MEDICAL COLLEGE,COIMBATORE

 

History of the department

v  The Biochemistry Department has started functioning separately from Physiology in the college premises since 1967.

v  Biochemistry Laboratory is functioning since 1964 initially in the college premises, later started functioning in  the hospital.

v  We provide emergency services in addition to the regular diagnostic services round the clock

Milestones of the department

 A . Hospital laboratory

*     Hospital Biochemistry Laboratory  is functioning since 1964.

*     Initially, the hospital lab was equipped with Photoelectric Colorimeter and Centrifuges only .

*     Later on during 1996 Semi auto analysers and Flame photometers, automated pipettes,Spectrophotometer were purchased.

*     Since 2000, The Fully Automated analyser, Electrolyte analysers [ion selective electrodes] were used for diagnostic works

*     Then Thyroid hormones analysis was started using Elisa Reader from 2004.

*     Arterial blood gas analysis was done using Blood Gas analyser since 2005.

*     The utilization of ISE 4000 Bicarbonate analyser & EM 360 Biochemical analyser commenced from 2009.

*     The Reverse osmosis plant was installed in our diagnostic laboratory in 2010.

        We have effective means of Biomedical waste management     

        functioning in our laboratory since 2011

LIST OF SOPHISTICATED INSTRUMENTS FOR BIOCHEMICAL ANALYSIS:

  •      FULLY AUTOMATED ANALYSER
  •      SEMI AUTOMATED ANALYSERS
  •      ELECTROLYTE ANALYSER
  •      ELISA.READER & WASHER
  •       ELECTROPHORETIC APPARATUS
  •      CHROMATOGRAPHY CHAMBER
  •      HOT AIR OVENS
  •      WATER.DISTILLATION APPARATUS
  •      CENTRIFUGES
  •      FLAME PHOTOMETERS
  •      BICARBONATE ANALYSER.
  •      BLOOD GAS ANALYSER

 BIOCHEMICAL  INVESTIGATIONS PERFORMED IN OUR LABORATORY:

   1.     Blood glucose

2.     Blood Urea

3.     Serum Creatinine

4.     Serum Total Protein

5.     Serum Albumin : Globulin

6.     Serum Cholesterol

7.     Serum Bilirubin - Total,  Direct

8.     S.G.O.T. (AST)

9.     S.G.P.T. (ALT)

10.   Serum Alkaline Phosphatase

11.   Serum Acid Phosphatase

12.   Serum Calcium

13.   Serum Phosphorus

14.   Serum Electrolytes(Na+, K+, Cl-, HCO3-, Li)

15.   Fluid Analysis (Protein, Sugar, Chloride)

16.   Urine - Sodium

17.   Glucose Tolerance Test.

18.   Clearance Tests -  Urea Clearance, Creatinine Clearance.

19.   Cerebro Spinal Fluid Analysis - Sugar,Chloride, Protein..

20.   Serum Total CPK, CPK- MB

21.   Serum LDH.

22.   Serum Triglycerides.

23.   Serum Amylase.

24.   Serum HDL Cholesterol, VLDL, LDL Cholesterol.

25.   Serum Protein Electrophoresis.

26.   Screening for Metabolic Disorder - Urine Analysis

27.   Analysis of Calculi.

28.   Paper Chromatography  - Single &Double Dimension.

29.   Thyroid Profile - T3, T4, TSH

30.   Blood Gas Analysis- pH,  pO2, pCo2 , Base excess

AUTOMATED ANALYSERS

                                                 BIOCHEMISTRY LABORATORY

      BIOCHEMISTRY DEPARTMENT STATISTICS (INVESTIGATIONS)

YEAR

MAIN LAB

 

        EMERGENCY LAB

TOTAL  INVESTIGATIONS

 

2008

3,86,894

        59,833

4,46,727

2009

3,81,857

76,451

              4,58,008

2010

4,76,137

72,740

              5,48,877

2011-

4,13,455

95,706

5,09,161

2012 Till date

     3,63,002

81,395

4,44,397

                                                                                                 

 















 B- Academic activities in the college:

We have Lecture hall accommodating 200 students, Equipped with LCD Projector and audio visual aids.

Our Practical Laboratory which accommodates 90 Students, has Central gas connection since 2010 and granite top were laid for the practical Work Tables in the student and Research Lab during 2011.

 Courses

 Students intake per year

Affiliated University

 

M.B.B.S

 

200

 

The Tamil Nadu DR. M.G.R Medical University, Chennai

D.M.L.T

100

Affiliated to King Institute of Preventive medicine & Research, Chennai.

 

Emergency care technicians

20

Affiliated to King Institute of Preventive medicine & Research, Chennai.

Dialysis technicians

20

Affiliated to King Institute of Preventive medicine & Research, Chennai.

D Pharmacy

 

60

Affiliated to Board of Pharmacy         

a)M.B.B.S course:                             Student seatallotment-200

Thestudents intake has been increased to 150 from the year 2004.
Thestudents intake has been increased to 200 from the year 2022.

AUDIOVISUAL AIDS
  The Department is now equipped withthe following instruments, to aid in Teaching and Analytical work like

  • L C D
  • Computers
  • Lap Top
  • Slide Projector and
  • Over Head Projector

ACADEMIC ACTIVITIES

Facilitation of acquiring   knowledge in the following Areas-

  • Cell organisation, transport, signals

  •  Nutrition, minerals, vitamins

  • Molecular biology, genetic mutations ,recombinant DNA , gene  therapy etc

  • Enzymes, role in metabolism.

  • Proteins of transport & defence, disorders

  • Metabolism of carbohydrates, lipids, proteins & disorders

  • Organ function tests of liver, kidney, thyroid, pancreas, adrenal gland.

  • Hormonal actions and mechanisms

  • Analysis of biochemical parameters in diagnosis of diseases

 TEACHING METHODS   INCLUDE 

  •   LECTURES
  •   DISCUSSIONS
  •   DEMONSTRATIONS
  •   SEMINARS 
  •   INTEGRATEDTEACHING-HORIZONTAL& VERTICAL
  •   Self Directed Learning
  •   Small Group Discussion
  •   Early Clinic Exposure
  •   AETCOM
  •   Quiz    

 We Conducted BioQuiz for theFirst M.B.B.S Students and Prizes for the Winners and Certificates for theParticipants were distributed.

 

2.D.PHARMACY  COURSE:           200 hours     Student seat allotment- 60

*         This course was started from the year 1991 .

*     Theory lectures and practical  training are given to the students in theallotted 200 hours for Biochemistry.

    TEACHING   by LECTURES  & PRACTICAL CLASSES on the following aspects.

 Basics of  chemistry, metabolisms ofCarbohydrates,Lipids,Proteins,In born Errors,  Enzymolgy, Nutrition, Diagnostic Instruments,Function Tests, clinical Correlations.

 Practical procedures ofanalysis of solutions, urine, blood parameters Reagent preparations, Demonstrationof Instrument functioning etc.
  Evaluation   of students is done by periodical theory and practical tests and           

  University examination   -Theory  &   Practical   at the end of the Year.

           

 3. D.M.L.T  COURSE :    200 HOURS  PER YEAR- Student seat allotment-100

In the year 2004 the C.M.L.T course was started. 

D.M.L.T course was started from the year 2005.

About 100 students are trained in laboratory technology every year.

Theory lectures and practical training are given to the students in the allotted hours for Biochemistry and paraclinical training in the diagnostic works at the hospital

 Basics of chemistry,metabolisms of Carbohydrates, Lipids, Proteins, In born Errors, Enzymolgy,Nutrition, Diagnostic Instruments, Function Tests., clinical  Correlations. Practical proceduresof analysis of solutions,urine,blood parameters, Reagent preparations,Standardisation of Reagents, preservation of samples

  Diagnostic procedures inthe hospital Laboratory are included in the syllabus.

   Universityexamination   -Theory   &  Practical   at the end of the 2 ndYear.

1.    PARAMEDICAL COURSE -10 HRS    

    Basics of    chemistry,metabolisms of Carbohydrates, Lipids, Proteins

 In born Errors ,  Enzymolgy,  Nutrition, Diagnostic Instruments, Function Tests., clinical Correletions are enlightened.                                                      

 

 
COMPLETED PROJECTS

S.NO

PROJECTS

YEAR

NAME

1.

PREVALENCE OF INTERLEUKIN 7 RECEPTOR ALPHA THR244ILE GENETIC POLYMORPHISM AMONG BREAST CANCER PATIENTS.

2017-2020

Dr. RAJESH WILSON

2.

A STUDY OF ASSOCIATIONOF HIGH SERUM PROLACTIN LEVELS WITH OTHER BIOCHEMICAL PARAMETERS IN PREECLAMPSIA.

2017-2020

Dr. DANIA TAMILSELVI

3.

SERUM GHRELIN LEVELS IN HYPOTHYROID PATIENTS.

2017-2020

Dr. P. SUMATHI

4.

PREDICTIVE VALUE OF “SERUM FETUIN – A” IN THE ASSESSMENT OF DISEASE SEVERITY IN ALCOHOLIC LIVER CIRRHOSIS.

2018-2021

Dr. B. ANITHA

5.

STUDY OF METHYLENE TETRAHYDRO FOLATE REDUCTASE(MTHFRC677T) SINGLE NUCLEOTIDE POLYMORPHISM IN PREECLAMPSIA.

2018-2021

Dr. S. VINITHA

6.

CORRELATION OF MEAN PLATELET VOLUME WITH GLYCEMIC INDEX IN PATIENTS WITH TYPE2 DM IN A TERTIARY CARE HOSPITAL

2018-2021

Dr. B. ANITHA

7.

AN UNUSUAL PRESENTATION OF VITAMIN-D DEFICIENCY – A CASE REPORT

2018-2021

Dr. B. ANITHA

8.

SERUM ADENOSINE DEAMINASE ACTIVITY IN CHRONIC LIVER DISEASE

2018-2021

Dr. B. ANITHA

9.

VITAMIN D SUPPLEMENTATION IN A PATIENT WITH POLYCYSTIC OVARIES OF ASSOCIATED MENSTRUAL DYSREGULATION -A CASE REPORT

2018-2021

Dr. S. VINITHA

10.

ASSOCIATION OF LIPID PROFILE AND HbA1C IN GOOD AND POOR GLYCEMIC CONTROL TYPE 2 DIABETES MELLITUS PATIENTS – A CROSS SECTIONAL STUDY
 

2018-2021

Dr. S. VINITHA

11.

ASSOCIATION BETWEEN THYROID HORMONES & LIPID PROFILE IN TYPE 2 DIABETES MELLITUS PATIENTS – A CASE CONTROL STUDY IN TERTIARY CARE HOSPITAL

2018-2022

Dr. P. PANKAJAM

S.NO

PROJECTS

YEAR

NAME

12.

ELEVATED PSEUDOCHOLINESTERASE LEVELS IN HYPERTHYROIDISM

2019-2022

Dr.NIVEDHA.J.N

13.

 SERUM PROCALCITONIN LEVELS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND IN ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN COIMBATORE POPULATION – AN OBSERVATIONAL STUDY

2019-2022

Dr.C.LAKSHMI

 
 
ONGOING PROJECTS

S.NO

PROJECTS

YEAR

NAME

1.

ROLE OF ADIPONECTIN AS AN INFLAMMATORY MARKER IN ASSESSING DISEASE SEVERITY IN RHEUMATOID ARTHRITIS

2018-2022

Dr. P. PANKAJAM

2.

SERUM NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN AS AN EARLY MARKER OF ACUTE KIDNEY INJURY IN SNAKE BITE – AN OBSERVATIONAL STUDY

2019-2022

Dr.C.LAKSHMI

3.

ELUCIDATING THE ROLE OF HEART TYPE FATTY ACID BINDING PROTEIN IN CARDIOVASCULAR DISEASES.

2019-2022

Dr.NIVEDHA.J.N

4.

COPEPTIN IN CHRONIC LIVER DISEASE.

2019-2022

Dr.SRISHANMUGAPRIYA.V

5.

SERUM VISFATIN IN RHEUMATOID ARTHRITIS.

2020-2023

Dr.SATHIYANINDHINI.M

6.

CIRCULATING ANGIOPOIETIN LIKE PROTEINS 3,8 LEVELS IN HYPOTHYROIDISM.

2020-2023

Dr.SUGUNA.R

7.

SERUM VISCERAL ADIPOSE TISSUE DERIVED SERINE PROTEASE INHIBITOR(VISFATIN) LEVELS AND ITS RELATION WITH HbA1C IN TYPE 2 DIABETES MELLITUS.

2020-2023

Dr.NALINI.P.S

9.

PSEUDOCHOLINESTERASE ACTIVITY IN PATIENTS WITH THYROID DISEASE

2019-2022

Dr.NIVEDHA.J.N

11.

SERUM URIC ACID LEVELS ON DIALYSIS EFFICACY AMONG CHRONIC RENAL FAILURE PATIENTS

2018-2022

Dr. P. PANKAJAM

13.

ELEVATED LIPID PROFILE AND PREVALENCE OF FATTY LIVER IN UNCONTROLLED HYPOTHYROIDISM- A CASE CONTROL STUDY

2019-2022

Dr.NIVEDHA.J.N

14.

INCREASED LEVELS OF INFLAMMATORY MARKERS INDICATE THE INFLUENCE OF DIABETES MELLITUS ON THE PROGNOSIS OF COVID 19 PATIENTS DURING THE SECOND WAVE IN A TERTIARY CARE CENTRE IN SOUTH INDIA

2019-2022

Dr.NIVEDHA.J.N

15.

TRANSIENT HYPERGLYCEMIA IN NEWLY DIAGNOSED PULMONARY TUBERCULOSIS PATIENTS -AN OBSERVATIONAL STUDY

2019-2022

Dr.C.LAKSHMI

16.

DOES SERUM ALBUMIN HAS AN IMPACT ON COVID -19 SEVERITY

2020-2023

Dr.SATHIYANINDHINI.M

S.NO

PROJECTS

YEAR

NAME

17.

SIGNIFICANCE OF SERUM URIC ACID LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS ATTENDING TERTIARY CARE HOSPITAL

2020-2023

Dr.SATHIYANINDHINI.M

18.

DYSLIPIDEMIA IN SUBCLINICAL HYPOTHYROIDISM IN PATIENTS OF COIMBATORE MEDICAL COLLEGE & HOSPITAL – A CASE CONTROL STUDY

2020-2023

Dr.SUGUNA.R

19.

PREVALENCE OF HYPOTHYROIDISM IN CHRONIC KIDNEY DISEASE – A CROSS SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL

2020-2023

Dr.NALINI.P.S

20.

STUDY OF CORRELATION BETWEEN SERUM SODIUM LEVELS AND SEVERITY OF CHRONIC LIVER DISEASE

2020-2023

Dr.NALINI.P.S

 
 
 
COIMBATORE MEDICAL COLLEGE AND HOSPITAL
DEPARTMENT OF BIOCHEMISTRY
BEST PAPERS/POSTERS
 

 

S.NO

PROJECT

PAPER/POSTER

AWARD YEAR

NAME

1.

DIABETES INFLUENCES PROGNOSIS OF COVID -19
BEST POSTER IN ANNUAL CONFERENCE OF ENDOCRINE SOCIETY OF TAMILNADU AND PUDUCHERRY 2021

POSTER

2021

Dr.NIVEDHA.J.N

2.

RELATIONSHIP BETWEEN SERUM PROCALCITONIN LEVELS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND IN ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN COIMBATORE POPULATION – AN OBSERVATIONAL STUDY
BEST ORAL PAPER IN NATIONAL AMBICON 2020

PAPER

2020

Dr.C.LAKSHMI

 
RECENT CME
AN UPDATE ON CURRENT APPROACH TO CARDIOVASCULAR DISEASES “
BY DEPARTMENT OF BIOCHEMISTRY COIMBATORE MEDICAL COLLEGE AND THE TAMILNADU DR.MGR MEDICAL UNIVERSITY-JANUARY 2020
ACHIEVEMENTS
1.Dr.Lakshmi.C,MD Biochemistry Postgraduate has won Best Paper award at the National Conference Of Association Of Medical M
                   2.Dr.Nivedha J N, MD Biochemistry Postgraduate has won third prize in Research Poster Presentation at the 9th Annual Conference of Endocrinology society of TamilNadu and Puducherry TRENDO 2021
QUIZ PRIZES
Our Final year M.D Biochemistry Postgraduates have won laurels in quiz conducted by  28th National Conference of Association of Medical Biochemists of India (AMBICON )2021
TEAM 1 : Dr.Pangajam P and Dr. Lakshmi C – won SECOND PRIZE
TEAM 2 : Dr.Nivedha JN and Dr. Srishanmugapriya.V – won FOURTH PRIZE
GUEST LECTURES – 2020-2021
1.Metabolic acidosis and Renal Tubular Acidosis – Dr. Prabakaran.,MD.,DM (Nephrology)
2.Inborn errors of metabolism – Dr. Senthilkumar.,MD.,DM. (Neonatology )
3.Routine and recent trends in Adrenal gland function tests – Dr.Thiyagarajan.,MBBS.,AB(Endocrinology)
4.Dialysis – Dr. Prabakaran.,MD.,DM(Nephrology)

 


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